MBD4 anticorps (AA 1-50)

N° du produit ABIN7453727

Détail du produit anti-MBD4 anticorps

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Épitope: AA 1-50

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Fonction: Rabbit anti-MBD4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MBD4

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Autre désignation: MBD4 (MBD4 Produits)

Synonymes: anticorps MED1, anticorps Med1, anticorps methyl-CpG binding domain 4, DNA glycosylase, anticorps methyl-CpG binding domain protein 4, anticorps methyl-CpG binding domain 4 DNA glycosylase, anticorps MBD4, anticorps Mbd4

Sujet: Background: MBD4 (methyl-CpG-binding domain protein 4) is a member of the MBD family of proteins that mainly functions to bind methylated CpG sites and to repress gene transcription. Unlike its family members, MBD4 exhibits thymine glycosylase activity and has been shown to play an important role in DNA mismatch repair and apoptosis.

ID gène: 8930

NCBI Accession: NP_003916

UniProt: O95243

Pathways: Réparation de l'ADN