RBM17 anticorps (AA 351-401)

N° du produit ABIN7453790

Détail du produit anti-RBM17 anticorps

Antigène: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Épitope: AA 351-401

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM17 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-SPF45 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 351 and 401

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RBM17

Antigène: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Autre désignation: SPF45 (RBM17 Produits)

Synonymes: anticorps zgc:55840, anticorps SPF45, anticorps 2700027J02Rik, anticorps RNA binding motif protein 17, anticorps RNA binding motif protein 17 L homeolog, anticorps Rbm17, anticorps rbm17, anticorps RBM17, anticorps rbm17.L

Sujet: Background: Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia [taken from the Universal Protein Resource (UniProt) Q96125].

ID gène: 84991

NCBI Accession: NP_116294

UniProt: Q96I25