OSR1 anticorps (AA 325-375)

N° du produit ABIN7454414

Détail du produit anti-OSR1 anticorps

Antigène: OSR1 (Odd-Skipped Related 1 (OSR1))

Épitope: AA 325-375

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OSR1 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-OSR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 325 and 375

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-OSR1 antibody A301-579A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur OSR1

Antigène: OSR1 (Odd-Skipped Related 1 (OSR1))

Autre désignation: OSR1 (OSR1 Produits)

Synonymes: anticorps XOsr1, anticorps odd, anticorps odd1, anticorps znf91, anticorps ODD, anticorps Odd1, anticorps Osr, anticorps OXSR1, anticorps zgc:101674, anticorps odd-skipped related transciption factor 1, anticorps odd-skipped related 1 (Drosophila), anticorps OSR1, anticorps osr1, anticorps Osr1

Sujet: Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.

ID gène: 9943

NCBI Accession: NP_005100

UniProt: O95747

Pathways: Tube Formation