PAGR1 anticorps (AA 204-254)

N° du produit ABIN7454425

Détail du produit anti-PAGR1 anticorps

Antigène: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Épitope: AA 204-254

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAGR1 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 204 and 254

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-PA1 antibody A301-978A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PAGR1

Antigène: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Autre désignation: PA1 (PAGR1 Produits)

Synonymes: anticorps C16orf53, anticorps C25H16orf53, anticorps PA1, anticorps 2900092E17Rik, anticorps C77040, anticorps PAGR1, anticorps GAS, anticorps Pa1, anticorps PAXIP1 associated glutamate rich protein 1, anticorps PAXIP1 associated glutamate rich protein 1A, anticorps Paxip1-associated glutamate-rich protein 1, anticorps PAGR1, anticorps Pagr1a, anticorps Pagr1

Sujet: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

ID gène: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6