LAS1L anticorps (AA 200-250)

N° du produit ABIN7454509

Détail du produit anti-LAS1L anticorps

Antigène: LAS1L (LAS1-Like (LAS1L))

Épitope: AA 200-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAS1L est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-LAS1L Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 200 and 250

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur LAS1L

Antigène: LAS1L (LAS1-Like (LAS1L))

Autre désignation: LAS1L (LAS1L Produits)

Synonymes: anticorps RGD1565755, anticorps Las1-like, anticorps dJ475B7.2, anticorps 1810030A06Rik, anticorps 5830482G23Rik, anticorps LAS1-like, ribosome biogenesis factor, anticorps LAS1 like, ribosome biogenesis factor, anticorps LAS1-like (S. cerevisiae), anticorps Las1l, anticorps LAS1L

Sujet: Background: LAS1L is involved in the biogenesis of the 60S ribosomal subunit. It is required for maturation of the 28S rRNA. LAS1L functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes [taken from the Universal Protein Resource (UniProt) Q9Y4W2].

ID gène: 81887

NCBI Accession: NP_112483

UniProt: Q9Y4W2