PALB2 anticorps (AA 675-725)

N° du produit ABIN7454733

Détail du produit anti-PALB2 anticorps

Antigène: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Épitope: AA 675-725

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PALB2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PALB2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 675 and 725

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PALB2

Antigène: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Autre désignation: PALB2 (PALB2 Produits)

Synonymes: anticorps PALB2, anticorps Fancn, anticorps si:ch211-14k19.9, anticorps FANCN, anticorps PNCA3, anticorps 4732427B05, anticorps BC066140, anticorps RGD1304759, anticorps partner and localizer of BRCA2, anticorps partner and localizer of BRCA2 L homeolog, anticorps PALB2, anticorps palb2, anticorps palb2.L, anticorps Palb2

Sujet: Background: PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

ID gène: 79728

NCBI Accession: NP_078951

UniProt: Q86YC2

Pathways: Réparation de l'ADN