WRNIP1 anticorps (AA 400-450)

N° du produit ABIN7454746

Détail du produit anti-WRNIP1 anticorps

Antigène: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Épitope: AA 400-450

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WRNIP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-WRNIP1 Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 400 and 450

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur WRNIP1

Antigène: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Autre désignation: WRNIP1 (WRNIP1 Produits)

Sujet: Background: WRNIP1 (Werner helicase interacting protein 1) was identified as a protein that interacts with the N-terminal region of Werner protein (WRN). WRN is a RecQ DNA helicase important to DNA repair and is the causative gene of Werner syndrome (WS), an autosomal recessive disease characterized by premature aging. WRNIP1 has been shown to interact with DNA polymerase delta (pol delta) and play a role in pol delta-mediated DNA synthesis. Additionally, WRNIP1 has been shown to interact with polyubiquitin chains indicating a link between ubiquitination and the DNA repair pathway.

ID gène: 56897

NCBI Accession: NP_064520

UniProt: Q96S55