CSTF2T anticorps (AA 566-616)
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- Antigène Voir toutes CSTF2T Anticorps
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
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Épitope
- AA 566-616
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CSTF2T est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Fonction
- Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified
- Homologie
- Mouse
- Purification
- Affinity Purified
- Immunogène
- between AA 566 and 616
- Isotype
- IgG
- Top Product
- Discover our top product CSTF2T Anticorps primaire
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- Indications d'application
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
- Autre désignation
- CSTF2T/TauCSTF64 (CSTF2T Produits)
- Synonymes
- anticorps 64kDa, anticorps C77975, anticorps tCstF-64, anticorps tauCstF-64, anticorps CstF-64T, anticorps cleavage stimulation factor, 3' pre-RNA subunit 2, tau, anticorps cleavage stimulation factor subunit 2 tau variant, anticorps cleavage stimulation factor subunit 2, tau variant, anticorps Cstf2t, anticorps CSTF2T
- Sujet
- Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
- ID gène
- 23283
- NCBI Accession
- NP_056050
- UniProt
- Q9H0L4
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