SF3A1 anticorps (AA 300-350)

N° du produit ABIN7454762

Détail du produit anti-SF3A1 anticorps

Antigène: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Épitope: AA 300-350

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3A1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-SF3a120/SAP114 Antibody, Affinity Purified

Homologie: Bovine

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SF3A1

Antigène: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Autre désignation: SF3a120/SAP114 (SF3A1 Produits)

Synonymes: anticorps Dmel\\CG16941, anticorps SF3a1, anticorps SF3a120, anticorps DDBDRAFT_0168938, anticorps DDBDRAFT_0233180, anticorps DDB_0168938, anticorps DDB_0233180, anticorps 1200014H24Rik, anticorps 5930416L09Rik, anticorps AI159724, anticorps si:dz150f13.2, anticorps wu:fc38e01, anticorps wu:fc50a11, anticorps wu:fj37c05, anticorps zgc:65786, anticorps PRP21, anticorps PRPF21, anticorps SAP114, anticorps SF3A120, anticorps CG16941 gene product from transcript CG16941-RA, anticorps SWAP/Surp domain-containing protein, anticorps splicing factor 3a, subunit 1, anticorps splicing factor 3a subunit 1, anticorps CG16941, anticorps sf3a1, anticorps spl1, anticorps Sf3a1, anticorps SF3A1

Sujet: Background: SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.

ID gène: 10291

NCBI Accession: NP_005868

UniProt: Q15459

Pathways: Ribonucleoprotein Complex Subunit Organization