EML4 anticorps (AA 931-981)

N° du produit ABIN7454794

Détail du produit anti-EML4 anticorps

Antigène: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Épitope: AA 931-981

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EML4 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-EML4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 931 and 981

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur EML4

Antigène: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Autre désignation: EML4 (EML4 Produits)

Synonymes: anticorps eml4, anticorps MGC89332, anticorps EML4, anticorps C2orf2, anticorps ELP120, anticorps EMAP-4, anticorps EMAPL4, anticorps ROPP120, anticorps 4930443C24Rik, anticorps AI644019, anticorps echinoderm microtubule associated protein like 4, anticorps echinoderm microtubule associated protein like 4 S homeolog, anticorps Eml4, anticorps EML4, anticorps eml4, anticorps eml4.S

Sujet: Background: Echinoderm microtubule associated protein like 4 (EML4) has been identified as part of a gene fusion with the kinase domain of the anaplastic lymphoma receptor tyrosine kinase (ALK) in non-small cell lung cancer. EML4 associates with in vitro polymerized microtubules. In the cell, phosphorylated EML4 associates with the mitotic spindle and is essential for proliferation and microtubule network formation.

ID gène: 27436

NCBI Accession: NP_061936

UniProt: Q9HC35