FOXL2 anticorps

N° du produit ABIN719156

Détail du produit anti-FOXL2 anticorps

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXL2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXL2

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Références pour anticorps anti-FOXL2 (ABIN719156)

Liu, Meng, Wang, Yang, Zhang, Tang: "FOXL2 suppresses proliferation, invasion and promotes apoptosis of cervical cancer cells." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 4, pp. 1534-43, (2014) (PubMed).

Détails sur FOXL2

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Autre désignation: FOXL2 (FOXL2 Produits)

Synonymes: anticorps BPES, anticorps BPES1, anticorps PFRK, anticorps PINTO, anticorps POF3, anticorps AU045128, anticorps Pfrk, anticorps FOXL2, anticorps zgc:136549, anticorps foxl2, anticorps FoxL2, anticorps foxL2, anticorps forkhead box L2, anticorps forkhead box L2a, anticorps forkhead box L2 S homeolog, anticorps forkhead transcription factor L2, anticorps foxl2 protein, anticorps fork-head box L2 transcription factor, anticorps FOXL2, anticorps Foxl2, anticorps foxl2a, anticorps foxl2, anticorps foxl2.S, anticorps LOC751846, anticorps foxL2

Sujet:

Synonyms: blepharophimosis, Blepharophimosis epicanthus inversus and ptosis 1, Blepharophimosis epicanthus inversus and ptosis, BPES 1, BPES, BPES1, epicanthus inversus and ptosis 1, forkhead box L2, Forkhead box protein L2, forkhead transcription factor FOXL2, FOX L2, FOXL 2, FOXL2, FOXL2_HUMAN, PFRK, PINTO, POF 3, POF3.

Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Poids moléculaire: 45-50kDa

ID gène: 668

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity