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UBR4 anticorps (AA 1350-1400)

UBR4 Reactivité: Humain, Souris WB, IP, IHC (fp) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7454815
  • Antigène Voir toutes UBR4 Anticorps
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    Épitope
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1350-1400
    Reactivité
    • 23
    • 12
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 18
    • 4
    • 1
    Lapin
    Clonalité
    • 20
    • 3
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBR4 est non-conjugé
    Application
    • 11
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Fonction
    Rabbit anti-p600 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogène
    between AA 1350 and 1400
    Isotype
    IgG
    Top Product
    Discover our top product UBR4 Anticorps primaire
  • Indications d'application

    IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2-10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    12 months
  • Antigène
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    Autre désignation
    p600 (UBR4 Produits)
    Synonymes
    anticorps ZUBR1, anticorps RBAF600, anticorps p600, anticorps 1810009A16Rik, anticorps A930005E13Rik, anticorps D930005K06Rik, anticorps Gm1032, anticorps Gm1666, anticorps N28143, anticorps Zubr1, anticorps mKIAA0462, anticorps Rbaf600, anticorps ubiquitin protein ligase E3 component n-recognin 4, anticorps E3 ubiquitin-protein ligase UBR4, anticorps UBR4, anticorps Ubr4, anticorps LOC100511934
    Sujet
    Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
    ID gène
    23352
    NCBI Accession
    NP_065816
    UniProt
    Q5T4S7
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