TRPS1 anticorps (AA 1000-1050)

N° du produit ABIN7454931

Détail du produit anti-TRPS1 anticorps

Antigène: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Épitope: AA 1000-1050

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPS1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-TRPS1 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1000 and 1050

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TRPS1

Antigène: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Autre désignation: TRPS1 (TRPS1 Produits)

Synonymes: anticorps GC79, anticorps LGCR, anticorps AI115454, anticorps AI447310, anticorps D15Ertd586e, anticorps transcriptional repressor GATA binding 1, anticorps transcriptional repressor GATA binding 1 S homeolog, anticorps Trps1, anticorps TRPS1, anticorps trps1.S

Sujet: Background: Tricho-rhino-phalangeal syndrome type I protein (TRPS1) is a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of TRPS1 to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in the TRPS1 gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III [taken from NCBI Entrez Gene (Gene ID: 7227)].

ID gène: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus