PSMD1 anticorps (AA 1-50)
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- Antigène Voir toutes PSMD1 Anticorps
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
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Épitope
- AA 1-50
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSMD1 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Fonction
- Rabbit anti-PSMD1 Antibody, Affinity Purified
- Homologie
- Orangutan
- Purification
- Affinity Purified
- Immunogène
- between AA 1 and 50
- Isotype
- IgG
- Top Product
- Discover our top product PSMD1 Anticorps primaire
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- Indications d'application
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
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- Antigène
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
- Autre désignation
- PSMD1 (PSMD1 Produits)
- Synonymes
- anticorps P112, anticorps Rpn2, anticorps S1, anticorps 2410026J11Rik, anticorps zgc:55818, anticorps psmd1, anticorps proteasome 26S subunit, non-ATPase 1, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 1, anticorps proteasome 26S subunit, non-ATPase 1 L homeolog, anticorps PSMD1, anticorps Psmd1, anticorps psmd1, anticorps psmd1.L
- Sujet
- Background: PSMD1 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 1] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD1 is the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5707)].
- ID gène
- 5707
- NCBI Accession
- NP_002798
- UniProt
- Q99460
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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