TNFSF8 anticorps

N° du produit ABIN7490486

Détail du produit anti-TNFSF8 anticorps

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFSF8 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Attributs du produit: Rabbit IgG

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt  1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur TNFSF8

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Autre désignation: CD30 Ligand (TNFSF8 Produits)

Synonymes: anticorps CD153, anticorps CD30LG, anticorps Cd30l, anticorps CD30L, anticorps TNFRSF8, anticorps TNFSF8, anticorps tumor necrosis factor (ligand) superfamily, member 8, anticorps TNF superfamily member 8, anticorps tumor necrosis factor superfamily member 8, anticorps Tnfsf8, anticorps TNFSF8

Sujet: CD30-L,CD153,TNFSF8,CD30L,CD30LG,CD153 antigen,CD30 antigen ligand,CD30 Ligand,
Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30 lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P32971