Thymic Stromal Lymphopoietin anticorps

N° du produit ABIN7490690

Détail du produit anti-Thymic Stromal Lymphopoietin anticorps

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Fragment: Fc fragment

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Thymic Stromal Lymphopoietin est non-conjugé

Application: Flow Cytometry (FACS)

Attributs du produit: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt  1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur Thymic Stromal Lymphopoietin

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Autre désignation: TSLP (TSLP Produits)

Synonymes: anticorps TSLP, anticorps thymic stromal lymphopoietin, anticorps TSLP, anticorps Tslp

Sujet: TSLP,
Description: This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c( ) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.

UniProt: Q969D9