Recombinant CCR1 anticorps

N° du produit ABIN7490774

L’anticorps anti-CCR1 Chimeric Human est utilisé pour la détection de CCR1 dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour Recombinant CCR1 anticorps (ABIN7490774)

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Type d'anticorp: Recombinant Antibody

Fragment: Fc fragment

Reactivité: Humain

Hôte: Human, Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: DMC465

Détail du produit anti-CCR1 anticorps

Fonction: Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1:100, WB 1:1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CCR1

Sujet: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1,
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

UniProt: P32246