CCR6 anticorps (PE-Cy7)
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- Antigène Voir toutes CCR6 Anticorps
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CCR6 est conjugé à/à la PE-Cy7
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Application
- Flow Cytometry (FACS)
- Clone
- G034E3
- Isotype
- IgG2b, kappa
- Top Product
- Discover our top product CCR6 Anticorps primaire
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- Indications d'application
- The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
- Commentaires
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Matching Isotype Control: PE/Cyanine7 Mouse IgG2b, κ Isotype Control (ABIN7469798)
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Antigène
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- Autre désignation
- CD196/CCR6 (CCR6 Produits)
- Synonymes
- anticorps BN-1, anticorps C-C CKR-6, anticorps CC-CKR-6, anticorps CCR-6, anticorps CD196, anticorps CKR-L3, anticorps CKRL3, anticorps CMKBR6, anticorps DCR2, anticorps DRY6, anticorps GPR29, anticorps GPRCY4, anticorps STRL22, anticorps Cmkbr6, anticorps KY411, anticorps C-C motif chemokine receptor 6, anticorps chemokine (C-C motif) receptor 6, anticorps CCR6, anticorps Ccr6
- Sujet
- CKRL3, CMKBR6, GPR29, STRL22,GPRCY4,CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
- ID gène
- 1235
- UniProt
- P51684
- Pathways
- cAMP Metabolic Process
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