STEAP3 anticorps

N° du produit ABIN7464576

Détail du produit anti-STEAP3 anticorps

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP3 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2 cytoplasm extract

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.79 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur STEAP3

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Autre désignation: STEAP3 metalloreductase (STEAP3 Produits)

Synonymes: anticorps STEAP3, anticorps 1010001D01Rik, anticorps Tsap6, anticorps pHyde, anticorps AHMIO2, anticorps STMP3, anticorps TSAP6, anticorps dudlin-2, anticorps STEAP3 metalloreductase, anticorps STEAP family member 3, anticorps STEAP3, anticorps steap3, anticorps Steap3

Sujet: STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pH yde,Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Poids moléculaire: 55 kDa

ID gène: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis