PREX1 anticorps

N° du produit ABIN7464629

Détail du produit anti-PREX1 anticorps

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PREX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PREX1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: human PREX1-transfected 293T cells

Validation: Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PREX1

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Autre désignation: phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1 Produits)

Synonymes: anticorps MGC68772, anticorps P-REX1, anticorps G630042G04, anticorps Setd6, anticorps RGD1306534, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog, anticorps phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1, anticorps prex1.L, anticorps PREX1, anticorps prex1, anticorps Prex1

Sujet: Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 , P-REX1,The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq]

Poids moléculaire: 186 kDa

ID gène: 57580

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization