PC anticorps (C-Term)

N° du produit ABIN7465195

Détail du produit anti-PC anticorps

Antigène: PC (Pyruvate Carboxylase (PC))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PC est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), RNA-Binding Protein Immunoprecipitation (RIP)

Réactivité croisée: Humain, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human Pyruvate Carboxylase. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:857. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PC

Antigène: PC (Pyruvate Carboxylase (PC))

Autre désignation: pyruvate carboxylase (PC Produits)

Synonymes: anticorps BcDNA, anticorps BcDNA:GH06348, anticorps Dmel\\CG1516, anticorps PC, anticorps pyc, anticorps wu:fb82g08, anticorps wu:fj85g01, anticorps PCX, anticorps BA4157, anticorps Pc, anticorps Pcb, anticorps PCB, anticorps Pcx, anticorps Pyruvate carboxylase, anticorps pyruvate carboxylase b, anticorps PYruvate Carboxylase, anticorps pyruvate carboxylase, anticorps pyruvate carboxylase Pyr1, anticorps PCB, anticorps pcxb, anticorps pyc-1, anticorps PC, anticorps pyc, anticorps pyr1, anticorps CNF00650, anticorps PYC1, anticorps Ndas_1152, anticorps Ilyop_2503, anticorps Calni_0495, anticorps Ftrac_1004, anticorps Plabr_3574, anticorps Sgly_2936, anticorps Celly_0558, anticorps Hipma_0131, anticorps Halhy_1567, anticorps Mesop_1269, anticorps Pcx, anticorps Pc

Sujet: Pyruvate carboxylase , PCB,This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

Poids moléculaire: 130 kDa

ID gène: 5091

UniProt: P11498