POT1 anticorps

N° du produit ABIN7465387

Détail du produit anti-POT1 anticorps

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human POT1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: protection of telomeres 1 (POT1 Produits)

Synonymes: anticorps HPOT1, anticorps POT1, anticorps DKFZp469P1825, anticorps pot1, anticorps 1500031H18Rik, anticorps AI851169, anticorps Pot1, anticorps Pot1a, anticorps protection of telomeres 1, anticorps protection of telomeres 1 L homeolog, anticorps protection of telomeres 1A, anticorps POT1, anticorps pot1.L, anticorps Pot1a, anticorps Pot1

Sujet: Protection of telomeres 1 , CMM10 , GLM9 , HPOT1,This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq]

Poids moléculaire: 71 kDa

ID gène: 25913

UniProt: Q9NUX5

Pathways: Cycle Cellulaire, Telomere Maintenance