CAPN10 anticorps

N° du produit ABIN7465701

Détail du produit anti-CAPN10 anticorps

Antigène: CAPN10 (Calpain 10 (CAPN10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPN10 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Calpain 10. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CAPN10

Antigène: CAPN10 (Calpain 10 (CAPN10))

Autre désignation: calpain 10 (CAPN10 Produits)

Synonymes: anticorps CAPN10, anticorps CANP10, anticorps NIDDM1, anticorps AW049679, anticorps Capn8, anticorps mKIAA1845, anticorps calpain 10, anticorps calpain 10 L homeolog, anticorps CAPN10, anticorps capn10.L, anticorps capn10, anticorps Capn10

Sujet: Calpain 10 , CANP10 , NIDDM1,Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Poids moléculaire: 75 kDa

ID gène: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion