CKMT1A anticorps

N° du produit ABIN7465720

Détail du produit anti-CKMT1A anticorps

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299 , HeLa

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CKMT1A

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Autre désignation: creatine kinase, mitochondrial 1A (CKMT1A Produits)

Synonymes: anticorps CKMT1, anticorps Mt-CK, anticorps ScCKmit, anticorps UbCKmit, anticorps mi-CK, anticorps Ckmt1, anticorps CKMT1B, anticorps Mia-CK, anticorps U-MtCK, anticorps creatine kinase, mitochondrial 1A, anticorps creatine kinase U-type, mitochondrial-like, anticorps creatine kinase, mitochondrial 1, ubiquitous, anticorps creatine kinase U-type, mitochondrial, anticorps CKMT1A, anticorps LOC100228000, anticorps Ckmt1, anticorps LOC100725326

Sujet: Creatine kinase, mitochondrial 1A , CKMT1 , U-MtCK , mia-CK,Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq]

Poids moléculaire: 47 kDa

ID gène: 548596

UniProt: P12532