TREX1 anticorps

N° du produit ABIN7466063

Détail du produit anti-TREX1 anticorps

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TREX1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human TREX1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TREX1

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Autre désignation: three prime repair exonuclease 1 (TREX1 Produits)

Synonymes: anticorps AGS1, anticorps CRV, anticorps DRN3, anticorps HERNS, anticorps 1661, anticorps AU041952, anticorps RGD1309596, anticorps three prime repair exonuclease 1, anticorps CpipJ_CPIJ012074, anticorps Tsp_03749, anticorps TREX1, anticorps Trex1

Sujet: Three prime repair exonuclease 1 , AGS1 , CRV , DRN3 , HERNS,This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Poids moléculaire: 39 kDa

ID gène: 11277

UniProt: Q9NSU2

Pathways: Apoptose