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IGF2R anticorps (AA 2201-2400)

IGF2R Reactivité: Humain ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN719711
  • Antigène Voir toutes IGF2R Anticorps
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Épitope
    • 15
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2201-2400
    Reactivité
    • 88
    • 36
    • 19
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 67
    • 23
    Lapin
    Clonalité
    • 66
    • 24
    Polyclonal
    Conjugué
    • 46
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGF2R est non-conjugé
    Application
    • 35
    • 32
    • 27
    • 23
    • 14
    • 12
    • 12
    • 10
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human IGF2R/Mannose 6 Phosphate Receptor
    Isotype
    IgG
    Top Product
    Discover our top product IGF2R Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Geng, Yang, Li, Song, Liu, Qiu, Liu, Yang: "Insulin-like growth factor-2 enhances functions of antigen (Ag)-specific regulatory B cells." dans: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17941-50, (2014) (PubMed).

    Yang, Liu, Li, Wen, Zhu, Xu: "Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis." dans: Cell biochemistry and biophysics, (2014) (PubMed).

  • Antigène
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Autre désignation
    IGF2R (IGF2R Produits)
    Synonymes
    anticorps CD222, anticorps CIMPR, anticorps M6P-R, anticorps MPR1, anticorps MPRI, anticorps AI661837, anticorps CI-MPR, anticorps M6P/IGF2R, anticorps Mpr300, anticorps mpri, anticorps cd222, anticorps cimpr, anticorps m6p-r, anticorps insulin like growth factor 2 receptor, anticorps insulin-like growth factor 2 receptor, anticorps IGF2R, anticorps Igf2r, anticorps igf2r
    Sujet

    Synonyms: Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222, IGF2R, MPRI

    Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

    ID gène
    3482
    UniProt
    P11717
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