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Myosin IA anticorps

MYO1A Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7466482
  • Antigène Voir toutes Myosin IA (MYO1A) Anticorps
    Myosin IA (MYO1A)
    Reactivité
    • 14
    • 10
    • 9
    Humain
    Hôte
    • 14
    • 1
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Myosin IA est non-conjugé
    Application
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human Myosin 1A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MYO1A Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Jurkat , Raji , K562 , NCI-H929

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.68 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    Myosin IA (MYO1A)
    Autre désignation
    myosin IA (MYO1A Produits)
    Synonymes
    anticorps CG7438, anticorps Dm IA, anticorps DmIA, anticorps Dmel\\CG7438, anticorps DroMIA, anticorps IA, anticorps MYOIA, anticorps Myo-IA, anticorps Myo1A, anticorps MyoIA, anticorps MyoID, anticorps myoID, anticorps souther, anticorps bbmi, anticorps mihc, anticorps myhl, anticorps dfna48, anticorps MGC83822, anticorps MYO1A, anticorps MGC79641, anticorps BBMI, anticorps DFNA48, anticorps MIHC, anticorps MYHL, anticorps BBM-I, anticorps Myhl, anticorps Myh1, anticorps Myosin 31DF, anticorps myosin IA L homeolog, anticorps myosin IA, anticorps Myo31DF, anticorps myo1a.L, anticorps MYO1A, anticorps myo1a, anticorps Myo1a
    Sujet
    Myosin IA , BBMI , DFNA48 , MIHC , MYHL,The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein encoded by this gene envelops an actin core bundle that, by comparison, is static in structure. [provided by RefSeq]
    Poids moléculaire
    118 kDa
    ID gène
    4640
    UniProt
    Q9UBC5
    Pathways
    Sensory Perception of Sound
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