CDC42EP2 anticorps

N° du produit ABIN7466857

Détail du produit anti-CDC42EP2 anticorps

Antigène: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC42EP2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse heart

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CDC42EP2

Antigène: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Autre désignation: CDC42 effector protein 2 (CDC42EP2 Produits)

Synonymes: anticorps CDC42EP2, anticorps zgc:103557, anticorps BORG1, anticorps CEP2, anticorps 1110008C05Rik, anticorps Borg1, anticorps Cep2, anticorps D19Bwg1013e, anticorps CDC42 effector protein 2, anticorps CDC42 effector protein 2 S homeolog, anticorps CDC42 effector protein (Rho GTPase binding) 2, anticorps CDC42EP2, anticorps cdc42ep2.S, anticorps cdc42ep2, anticorps Cdc42ep2

Sujet: CDC42 effector protein 2 , BORG1 , CEP2,CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]

Poids moléculaire: 22 kDa

ID gène: 10435

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization