X-Ray Repair Cross Complementing 5 (N-Term) anticorps
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- Antigène
- X-Ray Repair Cross Complementing 5
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Inconjugué
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- Protein G purified
- Immunogène
- Recombinant antigen containing the amino terminal portion of human Ku80 protein
- Clone
- 9403
- Isotype
- IgG1
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- Indications d'application
- WB: 1:1000-1:5000. ICC/IF: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: T24 , Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, No Preservative
- Agent conservateur
- Without preservative
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- X-Ray Repair Cross Complementing 5
- Synonymes
- anticorps KARP-1, anticorps KARP1, anticorps KU80, anticorps KUB2, anticorps Ku86, anticorps NFIV, anticorps AI314015, anticorps Ku80, anticorps X-ray repair cross complementing 5, anticorps X-ray repair complementing defective repair in Chinese hamster cells 5, anticorps XRCC5, anticorps Xrcc5
- Sujet
- X-ray repair cross complementing 5 , KARP-1 , KARP1 , KU80 , KUB2 , Ku86 , NFIV,The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
- Poids moléculaire
- 83 kDa
- ID gène
- 7520
- UniProt
- P13010
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