HIP1 anticorps

N° du produit ABIN7467610

Détail du produit anti-HIP1 anticorps

Antigène: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIP1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human HIP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse brain , rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.56 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur HIP1

Antigène: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Autre désignation: huntingtin interacting protein 1 (HIP1 Produits)

Synonymes: anticorps HIP-I, anticorps ILWEQ, anticorps CG10971, anticorps Dmel\\CG10971, anticorps Hip1R, anticorps 2610109B09Rik, anticorps A930014B11Rik, anticorps E130315I21Rik, anticorps mKIAA4113, anticorps huntingtin interacting protein 1, anticorps Huntingtin interacting protein 1, anticorps HIP1, anticorps Hip1, anticorps hip1

Sujet: Huntingtin interacting protein 1 , HIP-I , ILWEQ , SHON , SHONbeta , SHONgamma,The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]

Poids moléculaire: 116 kDa

ID gène: 3092

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity