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PABPC4 anticorps

PABPC4 Reactivité: Humain WB, IHC (p), IHC (wm) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7467853
  • Antigène Voir toutes PABPC4 Anticorps
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    Reactivité
    • 37
    • 14
    • 14
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 1
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PABPC4 est non-conjugé
    Application
    • 30
    • 17
    • 12
    • 7
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
     Réactivité croisée
    Humain, Souris, Poisson zèbre (Danio rerio)
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human PABPC4. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PABPC4 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    Autre désignation
    poly(A) binding protein cytoplasmic 4 (PABPC4 Produits)
    Synonymes
    anticorps cb12, anticorps sb:cb12, anticorps PABP, anticorps ePAB, anticorps ePABP, anticorps APP-1, anticorps APP1, anticorps PABP4, anticorps iPABP, anticorps polyadenylate-binding protein 4, anticorps poly(A) binding protein, cytoplasmic 4, anticorps poly(A) binding protein, cytoplasmic 4 (inducible form), anticorps poly(A) binding protein cytoplasmic 4 L homeolog, anticorps poly(A) binding protein cytoplasmic 4, anticorps Bm1_06880, anticorps Pabpc4, anticorps pabpc4, anticorps pabpc4.L, anticorps PABPC4
    Sujet
    Poly(A) binding protein cytoplasmic 4 , APP-1 , APP1 , PABP4 , iPABP,Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
    Poids moléculaire
    71 kDa
    ID gène
    8761
    UniProt
    Q13310
    Pathways
    SARS-CoV-2 Protein Interactome
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