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LIN7A anticorps

LIN7A Reactivité: Humain WB, IF, ICC Hôte: Souris Monoclonal GT377 unconjugated
N° du produit ABIN7468549
  • Antigène Voir toutes LIN7A Anticorps
    LIN7A (Lin-7 Homolog A (LIN7A))
    Reactivité
    • 30
    • 6
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 3
    Souris
    Clonalité
    • 29
    • 1
    Monoclonal
    Conjugué
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp LIN7A est non-conjugé
    Application
    • 26
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain
    Purification
    Affinity purified by Protein G.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human LIN7A. The exact sequence is proprietary.
    Clone
    GT377
    Isotype
    IgG2b
    Top Product
    Discover our top product LIN7A Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: MCF-7 , MDA-MB-231

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, No Preservative
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    LIN7A (Lin-7 Homolog A (LIN7A))
    Autre désignation
    lin-7 homolog A, crumbs cell polarity complex component (LIN7A Produits)
    Synonymes
    anticorps LIN-7A, anticorps LIN7, anticorps MALS-1, anticorps TIP-33, anticorps VELI1, anticorps lin7b, anticorps zgc:73090, anticorps AI848705, anticorps Veli, anticorps Veli1, anticorps lin-7 homolog A, crumbs cell polarity complex component, anticorps lin-7 homolog A (C. elegans), anticorps LIN7A, anticorps lin7a, anticorps Lin7a
    Sujet

    Synonyms: lin-7 homolog A, crumbs cell polarity complex component , LIN-7A , LIN7 , MALS-1 , MALS1 , TIP-33 , VELI1

    Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

    Poids moléculaire
    26 kDa
    ID gène
    8825
    UniProt
    O14910
    Pathways
    Synaptic Membrane
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