KMT5A anticorps

N° du produit ABIN7468629

Détail du produit anti-KMT5A anticorps

Antigène: KMT5A (N-Lysine Methyltransferase KMT5A (KMT5A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KMT5A est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Réactivité croisée: C. elegans, Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SETD8. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: U87-MG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur KMT5A

Antigène: KMT5A (N-Lysine Methyltransferase KMT5A (KMT5A))

Autre désignation: lysine methyltransferase 5A (KMT5A Produits)

Synonymes: anticorps KMT5A, anticorps PR-Set7, anticorps SET07, anticorps SET8, anticorps 2410195B05Rik, anticorps AA617402, anticorps AW536475, anticorps PR-SET7, anticorps lysine methyltransferase 5A, anticorps KMT5A, anticorps Kmt5a

Sujet:

Synonyms: lysine methyltransferase 5A , PR-Set7 , PR/SET07 , SET07 , SET8 , SETD8

Background: Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.

Poids moléculaire: 43 kDa

ID gène: 387893

UniProt: Q9NQR1