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NTAN1 anticorps (N-Term)

NTAN1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7469243
  • Antigène Voir toutes NTAN1 Anticorps
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    Épitope
    • 8
    • 7
    • 6
    • 4
    • 2
    N-Term
    Reactivité
    • 31
    • 12
    • 1
    Humain
    Hôte
    • 28
    • 3
    • 1
    Lapin
    Clonalité
    • 29
    • 3
    Polyclonal
    Conjugué
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NTAN1 est non-conjugé
    Application
    • 18
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human NTAN1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NTAN1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    Autre désignation
    NTAN1 (NTAN1 Produits)
    Synonymes
    anticorps PNAA, anticorps PNAD, anticorps N-terminal Asn amidase, anticorps N-terminal asparagine amidase, anticorps Ntan1, anticorps NTAN1
    Sujet

    Synonyms: N-terminal asparagine amidase , PNAA , PNAD

    Background: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.

    Poids moléculaire
    35 kDa
    ID gène
    123803
    UniProt
    Q96AB6
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