MBD5 anticorps
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- Antigène Voir toutes MBD5 Anticorps
- MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MBD5 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human MBD5. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product MBD5 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: HepG2 nuclear extract Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.19 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))
- Autre désignation
- MBD5 (MBD5 Produits)
- Synonymes
- anticorps MBD5, anticorps MRD1, anticorps 9430004D19Rik, anticorps AA536666, anticorps AI426407, anticorps C030040A15Rik, anticorps OTTMUSG00000012483, anticorps methyl-CpG binding domain protein 5, anticorps MBD5, anticorps mbd5, anticorps Mbd5
- Sujet
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Synonyms: methyl-CpG binding domain protein 5 , MRD1
Background: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq]
- Poids moléculaire
- 160 kDa
- ID gène
- 55777
- UniProt
- Q9P267
- Pathways
- Chromatin Binding
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