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MBD5 anticorps

MBD5 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7469295
  • Antigène Voir toutes MBD5 Anticorps
    MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))
    Reactivité
    • 14
    • 4
    • 1
    Humain
    Hôte
    • 10
    • 3
    Lapin
    Clonalité
    • 12
    • 2
    Polyclonal
    Conjugué
    • 10
    • 2
    • 1
    • 1
    Cet anticorp MBD5 est non-conjugé
    Application
    • 9
    • 8
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human MBD5. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MBD5 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: HepG2 nuclear extract Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.19 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))
    Autre désignation
    MBD5 (MBD5 Produits)
    Synonymes
    anticorps MBD5, anticorps MRD1, anticorps 9430004D19Rik, anticorps AA536666, anticorps AI426407, anticorps C030040A15Rik, anticorps OTTMUSG00000012483, anticorps methyl-CpG binding domain protein 5, anticorps MBD5, anticorps mbd5, anticorps Mbd5
    Sujet

    Synonyms: methyl-CpG binding domain protein 5 , MRD1

    Background: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq]

    Poids moléculaire
    160 kDa
    ID gène
    55777
    UniProt
    Q9P267
    Pathways
    Chromatin Binding
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