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GATSL3 anticorps

GATSL3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7469300
  • Antigène Tous les produits GATSL3
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    Reactivité
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 2
    Lapin
    Clonalité
    • 2
    Polyclonal
    Conjugué
    • 2
    Cet anticorp GATSL3 est non-conjugé
    Application
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: MCF-7 , MDA-MB-231

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.9 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    Autre désignation
    GATSL3 (GATSL3 Produits)
    Synonymes
    anticorps 2410008K03Rik, anticorps RGD1304774, anticorps cytosolic arginine sensor for mTORC1 subunit 1, anticorps GATS protein-like 3, anticorps CASTOR1, anticorps Gatsl3, anticorps Castor1
    Sujet

    Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3

    Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

    Poids moléculaire
    36 kDa
    ID gène
    652968
    UniProt
    Q8WTX7
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