GATSL3 anticorps
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- Antigène Tous les produits GATSL3
- GATSL3 (GATS Protein-Like 3 (GATSL3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GATSL3 est non-conjugé
- Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
- Isotype
- IgG
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anti-GATS Protein-Like 3 (GATSL3) (C-Term) antibody
GATSL3 Reactivité: Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: MCF-7 , MDA-MB-231
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.9 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- GATSL3 (GATS Protein-Like 3 (GATSL3))
- Autre désignation
- GATSL3 (GATSL3 Produits)
- Synonymes
- anticorps 2410008K03Rik, anticorps RGD1304774, anticorps cytosolic arginine sensor for mTORC1 subunit 1, anticorps GATS protein-like 3, anticorps CASTOR1, anticorps Gatsl3, anticorps Castor1
- Sujet
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Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3
Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
- Poids moléculaire
- 36 kDa
- ID gène
- 652968
- UniProt
- Q8WTX7
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