CD44 Standard anticorps (PE-Cy5)

N° du produit ABIN7470036

Détail du produit anti-CD44 Standard anticorps (PE-Cy5)

Antigène: CD44 Standard (CD44s)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 Standard est conjugé à/à la PE-Cy5

Application: Flow Cytometry (FACS)

Clone: OX-49

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Matching Isotype Control: PE/Cyanine5 Mouse IgG2a, κ Isotype Control (ABIN7469790)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur CD44 Standard

Antigène: CD44 Standard (CD44s)

Autre désignation: CD44H (CD44s Produits)

Sujet: Pgp-1, H-CAM, CD44s,CD44H,CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

ID gène: 12505

UniProt: P26051