BTLA anticorps

N° du produit ABIN7505891

Détail du produit anti-BTLA anticorps

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BTLA est non-conjugé

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD272 Purified

Specificité: The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.

Purification: Purified by protein-A affinity chromatography.

Immunogène: cells transfected with human CD272

Clone: MIH26

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2-5 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur BTLA

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Autre désignation: CD272 (BTLA Produits)

Synonymes: anticorps BTLA, anticorps BTLA1, anticorps CD272, anticorps A630002H24, anticorps B and T lymphocyte associated, anticorps BTLA, anticorps Btla

Sujet: B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1

ID gène: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints