BTLA anticorps (PE)
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- Antigène Voir toutes BTLA Anticorps
- BTLA (B and T Lymphocyte Associated (BTLA))
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Reactivité
- Humain, Non-Human Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BTLA est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Fonction
- Anti-Hu CD272 PE
- Specificité
- The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- cells transfected with human CD272
- Clone
- MIH26
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product BTLA Anticorps primaire
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- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- BTLA (B and T Lymphocyte Associated (BTLA))
- Autre désignation
- CD272 (BTLA Produits)
- Synonymes
- anticorps BTLA, anticorps BTLA1, anticorps CD272, anticorps A630002H24, anticorps B and T lymphocyte associated, anticorps BTLA, anticorps Btla
- Sujet
- B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
- ID gène
- 151888
- UniProt
- Q7Z6A9
- Pathways
- Cancer Immune Checkpoints
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