The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogène
DNA-immunization followed by a boost with CD307c transfected cells
FCRL3
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
anticorps CD307c, anticorps FCRH3, anticorps IFGP3, anticorps IRTA3, anticorps SPAP2, anticorps fcrh3, anticorps ifgp3, anticorps irta3, anticorps spap2, anticorps xfl1.2, anticorps Fc receptor like 3, anticorps Fc receptor-like 3 L homeolog, anticorps Fc receptor-like 3, anticorps Fc receptor-like 3 S homeolog, anticorps FCRL3, anticorps fcrl3.L, anticorps fcrl3, anticorps fcrl3.S
Sujet
Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3