The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogène
DNA-immunization followed by a boost with CD307d-transfected cells
FCRL4
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
anticorps CD307d, anticorps FCRH4, anticorps IGFP2, anticorps IRTA1, anticorps FCRL4, anticorps Fc receptor like 4, anticorps Fc receptor-like 4, anticorps Fc receptor-like 4 L homeolog, anticorps FCRL4, anticorps fcrl4, anticorps fcrl4.L
Sujet
Fc receptor like 4,CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.,FcRL4, FCRH4, IRTA1