Integrin alpha 1 anticorps (PE)

N° du produit ABIN7505936

Détail du produit anti-Integrin alpha 1 anticorps (PE)

Antigène: Integrin alpha 1 (ITGA1)

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin alpha 1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD49a PE

Specificité: The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: human CTL line

Clone: TS2-7

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur Integrin alpha 1

Antigène: Integrin alpha 1 (ITGA1)

Autre désignation: CD49a (ITGA1 Produits)

Synonymes: anticorps CD49A, anticorps E130012M19Rik, anticorps Vla1, anticorps CD49a, anticorps VLA1, anticorps integrin alpha 1, anticorps integrin subunit alpha 1, anticorps Itga1, anticorps ITGA1

Sujet: Integrin subunit alpha 1,CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.,alpha 1 integrin, VLA-1 alpha, ITGA1

ID gène: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex