CD51/CD61 anticorps (PE)

N° du produit ABIN7505942

Détail du produit anti-CD51/CD61 anticorps (PE)

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Reactivité: Humain, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51/CD61 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD51/CD61 PE

Specificité: The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.

Aucune reactivité croisée: Boeuf (Vache), Porc, Lapin

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: A cell suspension containing osteoclasts from osteoclastomas

Clone: 23C6

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Autre désignation: CD51/CD61 (ITGAV/ITGB3 Produits)

Synonymes: anticorps CD51, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps integrin subunit alpha V, anticorps ITGAV

Sujet: CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR