The mouse monoclonal antibody VIM15 recognizes an extracellular epitope of CD92, a 70 kDa transmembrane glycoprotein expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines.
anticorps CD92, anticorps CDW92, anticorps CHTL1, anticorps CTL1, anticorps RP11-287A8.1, anticorps Cdw92, anticorps Ctl1, anticorps 2210409B22Rik, anticorps 4833416H08Rik, anticorps AW547365, anticorps SLC44A1, anticorps slc44a1, anticorps zgc:112201, anticorps ctl1, anticorps solute carrier family 44 member 1, anticorps solute carrier family 44, member 1, anticorps solute carrier family 44 (choline transporter), member 1a, anticorps solute carrier family 44 (choline transporter), member 1, anticorps choline transporter-like protein 1, anticorps Choline transporter-like protein 1, anticorps solute carrier family 44 (choline transporter), member 1 L homeolog, anticorps SLC44A1, anticorps Slc44a1, anticorps slc44a1a, anticorps slc44a1, anticorps LOC100404101, anticorps chtl-1, anticorps slc44a1.L
Sujet
Solute carrier family 44 member 1,CD92 is a 70 kDa protein with ten transmembrane domains, intracellular N and C teminus, and two glycosylated larger extracellular loops. In the C-terminal domain, there is an ITIM-like sequence. This protein seems to be a choline transporter responsible for delivery of choline into the immune cells, to make it accessible for phospholipid synthesis, as well as a regulator of immune cell signaling. It is expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines. It can also be found on mast cells (but not eosinophils), and weakly on peripheral blood lymphocytes, fibroblasts, epithelial cells, and endothelial cells.,CTL1, CHTL1, SLC44A1