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GZMA anticorps

GZMA Reactivité: Humain IP, FACS, ICC Hôte: Souris Monoclonal CB9 unconjugated
N° du produit ABIN7505978
  • Antigène Voir toutes GZMA Anticorps
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    Reactivité
    • 52
    • 29
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 15
    • 3
    Souris
    Clonalité
    • 47
    • 15
    Monoclonal
    Conjugué
    • 26
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GZMA est non-conjugé
    Application
    • 33
    • 18
    • 13
    • 13
    • 12
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Fonction
    Anti-Hu Granzyme A Purified
    Specificité
    The mouse monoclonal CB9 recognizes granzyme A, a 28 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogène
    Full length human granzyme A
    Clone
    CB9
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product GZMA Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 5-10 μg/mL, intracellular staining.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    Autre désignation
    Granzyme A (GZMA Produits)
    Synonymes
    anticorps gzmA, anticorps GZMA, anticorps AW494114, anticorps Ctla-3, anticorps Ctla3, anticorps Hf, anticorps SE1, anticorps TSP-1, anticorps TSP1, anticorps CTLA3, anticorps HFSP, anticorps granzyme A, anticorps Granzyme A, anticorps granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3), anticorps gzmA, anticorps GZMA, anticorps graa, anticorps Gzma
    Sujet
    Granzyme A,Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B, granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity), and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA).,HFSP, CTLA3, GrA
    ID gène
    3001
    UniProt
    P12544
    Pathways
    Apoptose
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