IgE anticorps (APC)

N° du produit ABIN7505983

Détail du produit anti-IgE anticorps (APC)

Antigène: IgE

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IgE est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu IgE APC

Specificité: The mouse monoclonal antibody 4H10 reacts with human IgE, it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Purified human IgE.

Clone: 4H10

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 0.5-3 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur IgE

Antigène: IgE

Abstract: IgE Produits

Synonymes: anticorps IGH2, anticorps IgE, anticorps Gm900, anticorps immunoglobulin heavy chain (epsilon polypeptide), anticorps immunoglobulin heavy constant epsilon, anticorps Immunoglobulin heavy constant epsilon, anticorps Ighe, anticorps IGHE

Sujet: Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E