The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.
Purification
Purified by protein-A affinity chromatography.
Immunogène
DNA-immunization followed by a boost with CD307c transfected cells
anticorps CD307c, anticorps FCRH3, anticorps IFGP3, anticorps IRTA3, anticorps SPAP2, anticorps fcrh3, anticorps ifgp3, anticorps irta3, anticorps spap2, anticorps xfl1.2, anticorps Fc receptor like 3, anticorps Fc receptor-like 3 L homeolog, anticorps Fc receptor-like 3, anticorps Fc receptor-like 3 S homeolog, anticorps FCRL3, anticorps fcrl3.L, anticorps fcrl3, anticorps fcrl3.S
Sujet
Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3