IgE anticorps (APC)
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- Antigène Voir toutes IgE Anticorps
- IgE
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IgE est conjugé à/à la APC
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Application
- Flow Cytometry (FACS)
- Fonction
- Anti-Hu IgE APC
- Specificité
- The mouse monoclonal antibody 4H10 reacts with human IgE, it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).
- Purification
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- Purified human IgE.
- Clone
- 4H10
- Isotype
- IgG1
- Top Product
- Discover our top product IgE Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 0.5-3 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- IgE
- Abstract
- IgE Produits
- Synonymes
- anticorps IGH2, anticorps IgE, anticorps Gm900, anticorps immunoglobulin heavy chain (epsilon polypeptide), anticorps immunoglobulin heavy constant epsilon, anticorps Immunoglobulin heavy constant epsilon, anticorps Ighe, anticorps IGHE
- Sujet
- Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E
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