SIGLEC10 anticorps (Extracellular Domain)

N° du produit ABIN7506216

Détail du produit anti-SIGLEC10 anticorps

Antigène: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC10 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Fonction: Anti-Hu SIGLEC10 Purified

Specificité: The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.

Purification: Purified by protein-A affinity chromatography.

Immunogène: SIGLEC10 extracellular domain fused with human IgG1 Fc fragment

Clone: 5G6

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur SIGLEC10

Antigène: SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Autre désignation: SIGLEC10 (SIGLEC10 Produits)

Synonymes: anticorps PRO940, anticorps SIGLEC-10, anticorps SLG2, anticorps Siglecg, anticorps SIGLEC10, anticorps slg2, anticorps pro940, anticorps siglec-10, anticorps sialic acid binding Ig like lectin 10, anticorps sialic acid binding Ig-like lectin 10, anticorps sialic acid-binding Ig-like lectin 10, anticorps SIGLEC10, anticorps Siglec10, anticorps LOC484343, anticorps LOC100066644, anticorps siglec10, anticorps LOC100513863, anticorps LOC100340374

Sujet: Sialic acid binding Ig like lectin 10,SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.,PRO940, SGL2

ID gène: 89790

UniProt: Q96LC7