MIA2 anticorps (AA 268-360)

N° du produit ABIN721150

Détail du produit anti-MIA2 anticorps

Antigène: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Épitope: AA 268-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CTAGE5

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MIA2

Antigène: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Autre désignation: CTAGE5 (MIA2 Produits)

Synonymes: anticorps MEA6, anticorps MGEA, anticorps MGEA11, anticorps MGEA6, anticorps zgc:56047, anticorps melanoma inhibitory activity 2, anticorps CTAGE family, member 5, anticorps CTAGE family member 5, ER export factor, anticorps MIA2, anticorps ctage5, anticorps CTAGE5, anticorps Mia2

Sujet:

Synonyms: cTAGE 5A, cTAGE 5B, cTAGE 5C, cTAGE 5D, cTAGE family member 5, CTAGE family, member 5, CTAGE5, cTAGE5A, cTAGE5B, cTAGE5C, cTAGE5D, CTGE5_HUMAN, Cutaneous T cell lymphoma associated antigen 5, Cutaneous T-cell lymphoma-associated antigen 5, MEA11, MEA6, Meningioma expressed antigen 6 coiled coil proline rich, Meningioma expressed antigen 6/11, Meningioma-expressed antigen 6/11, MGEA, MGEA11, MGEA6, Protein cTAGE 5, Protein cTAGE-5.

Background: Cutaneous T cell lymphomas (CTCL) represent a group of malignancies that originate from CD4-T lymphocytes and manifest on the skin. CTCL is a general term for several neoplasms including mycosis fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell lymphoma associated-antigen 2) is a member of the cancer/testis antigen family of proteins (CTAGE) that, under normal conditions, are found primarily in the testis with little or no expression in other parts of the body. Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6, MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5 are expressed as multiple isoforms due to alternative splicing events.

ID gène: 4253